Ipamorelin

Description

Ipamorelin is a selective, synthetic pentapeptide that functions as a growth hormone secretagogue (GHS). Structurally, it mimics the action of ghrelin, the body’s natural “hunger hormone,” but with specific chemical alterations that enhance receptor selectivity. Researchers have identified this peptide as a potent agonist of the ghrelin/growth hormone secretagogue receptor (GHS-R1a), capable of triggering a significant pulse of growth hormone from the anterior pituitary gland.

Ipamorelin exhibits a high degree of specificity for the growth hormone axis. It stimulates the pituitary to release growth hormone without significantly elevating cortisol (stress hormone), prolactin, or stimulating the intense appetite response associated with other ghrelin mimetics. This unique selectivity allows for targeted research into growth hormone pulsatility without the confounding variables of stress response or hunger-induced metabolic shifts.

Key Research Applications

• Selective GH Secretion: Investigated heavily for its ability to mimic the body’s natural pulsatile release of growth hormone, promoting nitrogen retention and tissue repair without desensitizing the pituitary.

• Metabolic Recovery: Studies suggest Ipamorelin can accelerate the recovery of musculoskeletal tissue and improve body composition by shifting metabolism toward lipolysis, without the lipogenic (fat-storing) side effects of insulin spikes.

• Safety Profile & Specificity: Research distinguishes Ipamorelin from other secretagogues by its lack of impact on ACTH and cortisol plasma levels, making it a primary candidate for studies requiring a “clean” growth hormone stimulus.

⚠️ FOR RESEARCH PURPOSES ONLY This product is intended for laboratory research and development use only. It is not intended for human consumption, diagnostic, or therapeutic use. Handle with care and adhere to all laboratory safety protocols.